Patient: Male, 72 years old
Condition: Chronic venous leg ulcer (VLU), non-healing for 14 months
Treatment Site: Lower medial calf, left leg
Location: Dallas, Texas
Treatment Used: In-home application of amniotic skin substitute
Duration: 9 weeks total care, 4 applications

Background

The patient had a 14-month history of a non-healing venous leg ulcer on the lower left leg. Previous treatments included compression therapy, standard wound dressings, and topical antimicrobials—all of which failed to result in wound closure. The patient had limited mobility and declined surgical intervention. The wound caused persistent drainage, odor, and discomfort that disrupted daily activity and sleep.

Assessment & Initial Findings

Wound size: 4.8 cm x 3.2 cm

Tissue type: Slough with partial granulation

Wound bed: Moist, minimal healthy granulation

Surrounding skin: Inflamed, edematous

Pain score: 6/10

Due to the patient's non-response to traditional treatment and contraindication for surgery, our care team determined the patient was an ideal candidate for non-surgical wound healing with an amniotic membrane-based skin substitute.

Treatment Protocol

Initial Debridement & Prep: The wound was gently debrided in-home using conservative sharp technique and cleansed.

Amniotic Skin Substitute Application: The graft was applied directly to the wound bed and secured with a non-adherent secondary dressing and compression bandaging.

Follow-up Care: Repeated applications occurred every 2 weeks for a total of 4 grafts over 9 weeks.

Monitoring: Weekly wound assessments were conducted by the in-home wound care specialist.

Results

Week 3: Wound size reduced by 40%; pain decreased to 3/10

Week 6: Granulation tissue fully established; wound depth decreased by 75%

Week 9: Full epithelialization achieved; no signs of drainage or infection

The patient reported significant improvements in pain, mobility, and sleep. No adverse reactions occurred during or after treatment. The wound remained closed at a 30-day follow-up.

Key Takeaways

Amniotic skin substitutes offer a non-surgical path to closure for chronic leg wounds resistant to traditional care.

In-home application was essential for this patient’s access and compliance.

Rapid wound reduction and durable closure were achieved in less than 10 weeks.

Miracle Wound Rx is proud to support advanced, non-surgical healing options like amniotic graft therapy for patients who need personalized, home-based care.

📞 For more information, contact us at [email protected] or call (855) 480-0690.